Dostinex is a synthetic ergoline with a high affinity to dopamine D2 receptors, a strong prolonged activity inhibitor of prolactin secretion. Prolactin is a hormone that is released from the hypophysis. This medication is used to treat hormonal imbalance with much prolactin in the blood (hyperprolactinemia) to reduce or prevent breast milk production, except after childbirth (postpartum).
Take this medication exactly as prescribed by your doctor. Take it orally twice weekly. Dostinex is usually taken twice each week for at least 6 months. Dosage is adjusted generally at 4 week periods based on tests for prolactin levels in the blood.
Dostinex is contraindicated in patients with uncontrolled hypertension or known hypersensitivity to ergot derivatives (ergotamine, ergonovine, Ergomar, Cafergot, dihydroergotamine, Migranal Nasal Spray, D.H.E. 45, Ergotrate, or methylergonovine, Methergine, pulmonary, pericardial, cardiac valvular, or retroperitoneal fibrotic disorders in history.
Side effects may include symptoms of allergy (hives, rash, swelling of face and tongue, acne).
Major side effects are:
• cough or trouble breathing,
• feeling light-headed,
• fainting,
• nausea,
• vomiting,
• stomach pain,
• constipation,
• headache,
• numbness.
Contact your doctor if you experience severe symptoms listed above as you might need immediate medical help.
If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to make up a missed dose by taking an extra one.
If you suspect that you took too much of the medication seek for immediate medical attention. Your symptoms may appear as mental changes, nasal congestion, fainting, lightheadedness, or irregular heartbeat.
Store Dostinex in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.
